Title of article
Total synthesis of the antitumor agent (−)-laulimalide
Author/Authors
Mulzer، نويسنده , , Johann and Hanbauer، نويسنده , , Martin، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
3
From page
3381
To page
3383
Abstract
A stereocontrolled synthesis of the title compound is described. Key steps are an allylsilane addition to a chiral acetal as the major coupling step and a Yamaguchi macrolactonization for ring closure.
Keywords
Marine metabolites , macrolactonization , allylsilane addition , chiral acetal , Antitumor compounds
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1651468
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