Title of article
Enantioselective reduction of aryl ketones using LiBH4 and TarB-X: a chiral Lewis acid
Author/Authors
Suri، نويسنده , , Jeff T and Vu، نويسنده , , Truong and Hernandez، نويسنده , , Arturo and Congdon، نويسنده , , Julie and Singaram، نويسنده , , Bakthan، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
4
From page
3649
To page
3652
Abstract
High enantioselectivities are obtained using a tartaric acid-derived boronate ester in combination with lithium borohydride for asymmetric reduction of aryl ketones. The chiral Lewis acid, TarB-X, is easily prepared in 1 h, and the resulting alcohols are obtained in enantiomeric excesses of 88–99%.
Keywords
enantioselective , Tartaric acid , Boronic Acid , Reduction , chiral Lewis acid , asymmetric
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1651661
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