Title of article
Aryl epoxide–halohydrin transformations: stereochemistry of reactions of aryl epoxides with lithium halide–acetic acid reagent
Author/Authors
Bartas-Yacoubou، نويسنده , , Jeanne-Marie and Maduike، نويسنده , , Nkabuije and Kyere، نويسنده , , Sampson and Doan، نويسنده , , Lanxuan and Whalen، نويسنده , , Dale L.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
2
From page
3781
To page
3782
Abstract
The reactions of indene oxide (4a), 5-methoxyindene oxide (4b), 1,2,3,4-tetrahydronaphthalene-1,2-epoxide (5a) and 6-methoxy-1,2,3,4-tetrahydronaphthalene-1,2-epoxide (5b) with lithium halides in the presence of acetic acid (LiX/HOAc) yield mixtures of cis and trans halohydrins. These results are in contrast to those reported for the reactions of a series of aliphatic epoxides with LiX/HOAc, which proceed stereospecifically to yield only trans halohydrins.
Keywords
aryl epoxides , lithium halides , Chlorohydrins , Stereochemistry
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1651761
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