Title of article
Improvements of the total synthesis of monocillin I and radicicol via Miyaura–Suzuki couplings
Author/Authors
Tichkowsky، نويسنده , , Isabelle and Lett، نويسنده , , Robert، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
5
From page
4003
To page
4007
Abstract
The palladium-catalyzed coupling of the vinyldisiamylborane, formed in situ, affords the isocoumarins which can be used further for the synthesis of radicicol and related macrolides, in 72% global overall yield from the alkyne. Advantages over related vinylboronates or vinyltin couplings are discussed in the case of the present examples.
Keywords
Macrolides , Isocoumarins , boron and compounds , Suzuki reaction
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1651922
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