• Title of article

    Asymmetric synthesis of (+)-indatraline using rhodium-catalyzed C–H activation

  • Author/Authors

    Davies، نويسنده , , Huw M.L. and Gregg، نويسنده , , Timothy M.، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2002
  • Pages
    3
  • From page
    4951
  • To page
    4953
  • Abstract
    The potent monoamine reuptake inhibitor (+)-indatraline, 1, was prepared in greater than 98% ee employing a highly enantioselective carbenoid C–H insertion reaction into 1,4-cyclohexadiene catalyzed by the chiral rhodium complex, Rh2(S-DOSP)4.
  • Keywords
    indatraline , Dopamine transporter , C–H insertion , rhodium carbene , C–H activation
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2002
  • Journal title
    Tetrahedron Letters
  • Record number

    1652570