Title of article
Friedel–Crafts acylation of indoles in acidic imidazolium chloroaluminate ionic liquid at room temperature
Author/Authors
Yeung، نويسنده , , Kap-Sun and Farkas، نويسنده , , Michelle E and Qiu، نويسنده , , Zhilei and Yang، نويسنده , , Zhong، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
3
From page
5793
To page
5795
Abstract
A practical and convenient protocol has been developed for the acidic 1-ethyl-3-methylimidazolium chloroaluminate ionic liquid (generated from 1-ethyl-3-methylimidazolium chloride (EmimCl) and aluminium chloride (X(AlCl3), mole fraction X=0.67–0.75) promoted Friedel–Crafts acylation of indoles at room temperature. The simple experimental procedure provides 3-substituted indoles in good to high yields with less electron rich indole ring systems.
Keywords
imidazolium chloroaluminate , Ionic liquid , acylation , indole
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1653142
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