Title of article
Regioselective supramolecular catalysis. Exploiting multiple binding motifs in propanediurea molecular clips
Author/Authors
Bugnet، نويسنده , , Emmanuelle A. and Nixon، نويسنده , , Tracy D. and Kilner، نويسنده , , Colin A. and Greatrex، نويسنده , , Robert J. Kee، نويسنده , , Terence P.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
4
From page
5491
To page
5494
Abstract
Molecular clips derived from 2,4,6,8-tetraazabicyclo[3.3.1]nonane-3,7-dione promote increased regioselectivity in the SO2Cl2-mediated electrophilic aromatic chlorination of ortho-cresol leading to para/ortho ratios (Rp/o) <25; approximately six times larger than in the absence of the clip. Specific recognition events involving hydrogen-bond, π–π and dative covalent interactions are implicated.
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1653577
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