• Title of article

    Expedient synthesis of secondary amines bound to indole resin and cleavage of resin-bound urea, amide and sulfonamide under mild conditions

  • Author/Authors

    Bhattacharyya، نويسنده , , Sukanta and Gooding، نويسنده , , Owen W. and Labadie، نويسنده , , Jeff، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2003
  • Pages
    4
  • From page
    6099
  • To page
    6102
  • Abstract
    Highly efficient, new protocols for the attachment of primary amines to indole aldehyde resin using Ti(OiPr)4–NaBH4 and CH(OMe)3–NaBH3CN–HOAc are reported. Mild cleavage conditions for the release of urea, amide and sulfonamide products from the solid support using 1% trifluoroacetic acid (TFA) are developed.
  • Keywords
    indole aldehyde resin , Primary amines , reductive amination
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2003
  • Journal title
    Tetrahedron Letters
  • Record number

    1653835

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1653835