Title of article
C2-symmetrical sterol–polyether conjugates as highly efficient synthetic ionophores
Author/Authors
Avallone، نويسنده , , Elvira and Izzo، نويسنده , , Irene and Vuolo، نويسنده , , Gerardo and Costabile، نويسنده , , Monica and Garrisi، نويسنده , , Davide and Pasquato، نويسنده , , Lucia and Scrimin، نويسنده , , Paolo and Tecilla، نويسنده , , Paolo and De Riccardis، نويسنده , , Francesco، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
4
From page
6121
To page
6124
Abstract
A new class of artificial ionophores has been rationally designed and synthesized linking to a tetrafunctionalized l-treitol spacer two rigid hydrophobic 3β-hydroxy-5α-23,24-bisnorcholanic units and two flexible hydrophilic oligo(ethylene glycol) chains. Compounds 1a and 1b were incorporated into phospholipid vesicles and shown to facilitate Na+-transport.
Keywords
Steroid , ionophore , amphiphiles
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1653845
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