• Title of article

    Two-fold amino acid-based chiral aminophosphine–oxazolines and use in asymmetric allylic alkylation

  • Author/Authors

    Blanc، نويسنده , , Catherine and Hannedouche، نويسنده , , Jérôme and Agbossou-Niedercorn، نويسنده , , Francine، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2003
  • Pages
    5
  • From page
    6469
  • To page
    6473
  • Abstract
    Chiral aminophosphine–oxazoline ligands derived from two different amino acids (tetrahydroisoquinoline carboxylic acid and proline) have been synthesized and examined as chiral auxiliaries in asymmetric allylic alkylation of three substrates. Stereoisomers 1a and 2a are providing the highest enantioselectivities (up to 94% ee) in the allylation of diphenylpropenyl acetate.
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2003
  • Journal title
    Tetrahedron Letters
  • Record number

    1654085