The interaction mechanisms between Saccharomyces cerevisiae and menadione and its application in toxicology study

This study describes interaction mechanism between menadione and the yeast with the aid of the catabolite assay and the culture fluorescence method, with a view towards exploitting the potential of the mediator in toxicology study. Double mediator system containing menadione and the hydrophilic mediator, ferricyanide, was employed for evaluating the toxic effects of furfural on the yeast and the results showed the well consistence between the MICREDOX method and the conventional method.