Title of article
Stereoselective synthesis of the α-glucosidase inhibitor nectrisine
Author/Authors
Hulme، نويسنده , , Alison N. and Montgomery، نويسنده , , Charles H.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
5
From page
7649
To page
7653
Abstract
The α-glucosidase inhibitor nectrisine was synthesised in 12 steps (31% overall yield) starting from d-serine. The three contiguous stereocentres of this iminosugar were introduced via a highly diastereoselective boron mediated glycolate aldol reaction.
Keywords
Iminosugars , glycolate aldol , Glycosidase inhibitors
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1654959
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