Title of article
Terreusinone, a novel UV-A protecting dipyrroloquinone from the marine algicolous fungus Aspergillus terreus
Author/Authors
Lee، نويسنده , , Sang Mi and Li، نويسنده , , Xi Feng and Jiang، نويسنده , , Hualiang and Cheng، نويسنده , , Jia Gao and Seong، نويسنده , , Seeyearl and Choi، نويسنده , , Hong Dae and Son، نويسنده , , Byeng Wha Son، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
4
From page
7707
To page
7710
Abstract
A novel chiral dipyrrolobenzoquinone derivative, terreusinone (1), has been isolated as a potent UV-A protectant from the marine algicolous fungus Aspergillus terreus. The structure and absolute stereochemistry of the new compound was established by spectral interpretation, Horeauʹs method and quantum chemistry calculations as 2,6-bis[(1R)-1-hydroxyisobutyl]-1H,5H-pyrrolo[2,3-b]indole-4,8-dione (1). Compound 1 exhibited a UV-A absorbing activity with ED50 value of 70 μg/mL.
Keywords
Quantum chemistry calculation , Aspergillus terreus , marine algicolous fungus , terreusinone , dipyrroloquinone , UV-A protection
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1654991
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