Title of article
Application of chiral lithium amide bases to the thia-Sommelet dearomatization reaction
Author/Authors
McComas، نويسنده , , Casey C. and Van Vranken، نويسنده , , David L.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
3
From page
8203
To page
8205
Abstract
Thia-Sommelet dearomatization reactions of benzylsulfonium ylides can create highly congested quaternary centers. Chiral bis-lithium amide bases were shown to effect enantiotopic deprotonation of benzylsulfonium ions, leading to thia-Sommelet rearrangement. The chiral trienes were generated in up to 50% ee.
Keywords
sulfonium , Sigmatropic , Rearrangement , Enantioselectivity , Dearomatization
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1655334
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