Title of article
A highly stereocontrolled and efficient synthesis of α- and β-pseudouridines
Author/Authors
Hanessian، نويسنده , , Stephen and Machaalani، نويسنده , , Roger، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
3
From page
8321
To page
8323
Abstract
A five-step practical and stereocontrolled synthesis of α- and β-pseudouridines from d-ribonolactone is described. The key step involves a highly stereoselective reduction of a hemiketal C-nucleoside intermediate in each case. Multi-gram quantities of β-pseudouridine can now be made available.
Keywords
C-nucleoside , cycloetherification , selective reduction
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1655434
Link To Document