Title of article
An efficient palladium catalyzed synthesis of 2-arylbenzothiazoles
Author/Authors
Majo، نويسنده , , Vattoly J. and Prabhakaran، نويسنده , , Jaya and Mann، نويسنده , , J.John and Dileep Kumar، نويسنده , , J.S.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
3
From page
8535
To page
8537
Abstract
A novel and convergent palladium catalyzed synthesis of 2-arylbenzothiazoles has been investigated. The key step in the synthesis is a Suzuki biaryl coupling of 2-bromobenzothiazole with aryl boronic acids to provide a variety of 2-arylbenzothiazole derivatives in good yield. The synthetic utility of this methodology is demonstrated by the synthesis of 2-(4-aminophenyl)-6-methoxybenzothiazole, a PET probe precursor for the in vivo imaging of Alzheimerʹs disease.
Keywords
Boronic Acid , Suzuki coupling , PALLADIUM , benzothiazole
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1655574
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