Title of article
Asymmetric catalysis of ene reactions with trifluoropyruvate catalyzed by dicationic palladium(II) complexes
Author/Authors
Aikawa، نويسنده , , Kohsuke and Kainuma، نويسنده , , Satoshi and Hatano، نويسنده , , Manabu and Mikami، نويسنده , , Koichi، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
3
From page
183
To page
185
Abstract
Chiral dicationic SEGPHOS–Pd(II) complex achieves a high chemical yield, (E)-olefin selectivity, anti-diastereoselectivity, along with high enantioselectivity even with less reactive mono- and 1,2-disubstituted olefins in this much less reactive ketone–ene reactions. The high levels of enantioselectivity stem from the effective shielding with diphenyl groups on phosphines caused by the narrow dihedral angle of metal complexes with SEGPHOS.
Keywords
PALLADIUM , carbonyl–ene reaction , BINAP , SEGPHOS , trifluoropyruvate
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1656275
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