Title of article
Asymmetric total synthesis of octalactin B using a new and rapid lactonization
Author/Authors
Shiina، نويسنده , , Isamu and Oshiumi، نويسنده , , Hiromi and Hashizume، نويسنده , , Minako and Yamai، نويسنده , , Yu-suke and Ibuka، نويسنده , , Ryoutarou، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
5
From page
543
To page
547
Abstract
A method for the synthesis of octalactin B is established via a new and quite effective mixed-anhydride lactonization for the synthesis of an eight-membered ring moiety using 2-methyl-6-nitrobenzoic anhydride with DMAP. Both an optically active linear precursor of the lactone and a side chain of octalactins are prepared by the enantioselective aldol reaction of ketene silyl acetals with aldehydes.
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1656525
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