• Title of article

    Asymmetric synthesis of macrolactin analogue

  • Author/Authors

    Kobayashi، نويسنده , , Yusuke and Fukuda، نويسنده , , Akihiro and Kimachi، نويسنده , , Tetsutaro and Ju-ichi، نويسنده , , Motoharu and Takemoto، نويسنده , , Yoshiji، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2004
  • Pages
    4
  • From page
    677
  • To page
    680
  • Abstract
    Total asymmetric synthesis of macrolactin A analogue was accomplished by the convergent strategy. Rapid access to advanced intermediate 16 through isomerization of ynone to (E,E)-conjugated dienone is a key step of this synthesis. Overall, control of all of the four stereocenters was achieved by means of asymmetric and diastereoselective reactions without using any chiral natural sources.
  • Keywords
    asymmetric synthesis , Ynone , Isomerization , (e , E)-Conjugated dienone , macrolactin A , antibiotics , Antivirus
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2004
  • Journal title
    Tetrahedron Letters
  • Record number

    1656614