Title of article
Microwave assisted solvent free amination of halo-(pyridine or pyrimidine) without transition metal catalyst
Author/Authors
Narayan، نويسنده , , Sanjay and Seelhammer، نويسنده , , Troy and Gawley، نويسنده , , Robert E.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
3
From page
757
To page
759
Abstract
A solvent free direct amination of halo-(pyridine or pyrimidine) has been developed in good to high yields under computer-controlled microwave irradiation without transition metal catalyst. This reaction is a solvent and metal free, useful method for coupling of halo-(pyridine or pyrimidine) with pyrrolidine and piperidine derivatives by nucleophilic aromatic substitution (SNAr).
Keywords
SNAr , N-(Pyridyl)piperidine , Halopyridine , microwave , N-(Pyridyl)pyrrolidine , amination
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1656661
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