Title of article
Synthesis of potential bisubstrate inhibitors of Leishmania elongating α-d-mannosyl phosphate transferase
Author/Authors
Borodkin، نويسنده , , Vladimir S. and Ferguson، نويسنده , , Michael A.J and Nikolaev، نويسنده , , Andrei V.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
6
From page
857
To page
862
Abstract
Synthesis of a potential mechanism-based bisubstrate inhibitor 1 of the elongating α-d-mannosyl phosphate transferase in Leishmania, comprising a guanosine subunit bound to the synthetic acceptor substrate through the methylenebisphosphonate linker, as well as its analogues 2 and 3 has been successfully accomplished.
Keywords
carbohydrates , phosphonic acids and derivatives , transition states
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1656726
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