Title of article
Asymmetric alkylation of diphenylmethane derivatives using (−)-sparteine
Author/Authors
Wilkinson، نويسنده , , James A. and Rossington، نويسنده , , Stephen B. and Leonard، نويسنده , , John and Hussein، نويسنده , , Nigel، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
3
From page
1191
To page
1193
Abstract
Alkylation of 2-oxygenated diphenylmethane derivatives using sec-butyllithium and (−)-sparteine gave enantiomeric excesses of up to 60% with allyl bromide but alkylations with methyl electrophiles were poorly selective. When compounds with a free hydroxy in the 2-position were alkylated the selectivity was reversed.
Keywords
asymmetric , Alkylation , Deprotonation , Diphenylmethane , Sparteine
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1656954
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