Title of article
Synthesis of Latia luciferin benzoate analogues and their bioluminescent activity
Author/Authors
Nakamura، نويسنده , , Mitsuhiro and Masaki، نويسنده , , Mizuki and Maki، نويسنده , , Shojiro and Matsui، نويسنده , , Ryo and Hieda، نويسنده , , Minako and Mamino، نويسنده , , Masashi and Hirano، نويسنده , , Takashi and Ohmiya، نويسنده , , Yoshihiro and Niwa، نويسنده , , Haruki، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
3
From page
2203
To page
2205
Abstract
The bioluminescent system of the univalve shell Latia neritoides exhibits a luciferin–luciferase reaction. We study the enol formate structure of Latia luciferin, which is expected to be important for luminescent activity. The Latia luciferin analogues with an enol substituted benzoate moiety were synthesized and their bioluminescent activity was measured. The Latia luciferin benzoate analogues delay emission for natural luciferin in bioluminescence, indicating that the Latia bioluminescent activity can be controlled by the design of the enol ester.
Keywords
luciferin , Latia neritoides , luciferase , enol ester , Bioluminescence
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1657498
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