Title of article
Radical cyclizations to quinolone and isoquinolone systems under oxidative and reductive conditions
Author/Authors
Osornio، نويسنده , , Yazmin M. and Miranda، نويسنده , , Luis D. and Cruz-Almanza *، نويسنده , , Raymundo and Muchowski، نويسنده , , Joseph M.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
4
From page
2855
To page
2858
Abstract
Radical cyclizations to quinolone and isoquinolone systems under Fenton-type and n-Bu3SnH-mediated conditions are described. For N-iodoalkylquinolones, ca. 3:1 mixtures of oxidative cyclization products at C-2, and unexpectedly at C-8, were obtained under both conditions. Five- or six-membered oxidative cyclization products were obtained from N-iodoalkylisoquinolones under Fenton-type conditions, whereas n-Bu3SnH-mediated reactions gave products of reductive cyclization in the five, six, and seven-membered series.
Keywords
Isoquinolone , Quinolone , Fenton-type conditions , cyclization , radicals
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1657812
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