Title of article
Microwave assisted synthesis of 5-hydroxy-5-trichloromethyl-4,5-dihydroisoxazoles
Author/Authors
Martins، نويسنده , , Marcos A.P and Beck، نويسنده , , Paulo and Cunico، نويسنده , , Wilson and Pereira، نويسنده , , Claudio M.P and Sinhorin، نويسنده , , Adilson P and Blanco، نويسنده , , Rogerio and Maldonado Peres، نويسنده , , Rodrigo and Bonacorso، نويسنده , , Helio G and Zanatta، نويسنده , , Nilo، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
4
From page
7005
To page
7008
Abstract
A series of 13 5-hydroxy-5-trichloromethyl-4,5-dihydroisoxazoles have been synthesized in 78–96% yield by environmentally benign microwave induced techniques involving the cyclocondensation of 4-alkoxy-1,1,1-trichloro-3-alken-2-ones [CCl3C(O)C(R2)=C(R1)OR, where R2=H, alkyl; R1=H, alkyl, aryl and R=H, alkyl] with hydroxylamine using toluene as solvent. The advantages obtained by the use of microwave irradiation in relation to a classical method were demonstrated.
Keywords
halogen compounds , Isoxazoles , Microwave irradiations , enones
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1658206
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