Title of article
Unexpected highly regioselective macrocyclization of o-allylic N-carbonyl substituted anilines
Author/Authors
Javier Agejas، نويسنده , , Javier and Delgado، نويسنده , , Francisca and Vaquero، نويسنده , , Juan J. and Garc??a-Nav??o، نويسنده , , José L. and Lamas، نويسنده , , Carlos، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
3
From page
8025
To page
8027
Abstract
An unexpected bromocyclocarbamoylation of o-allylic N-BOC-anilines has been observed producing 2-oxo-3,1-benzoxazocine derivatives through an 8-endo-trig process, which on heating ring-transformed into a [6.5.5] tricyclic fused oxazolidinone compounds. A mixture of both heterocycles was obtained when the starting N-BOC anilines were heated with NBS in THF. The process seems to be general for related N-carbonyl substituted anilines.
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1658825
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