Title of article
A new strategy for 2-substituted indolylalkylamines: synthesis of 2-aryldihomotryptamines
Author/Authors
Nenajdenko، نويسنده , , Valentine G and Zakurdaev، نويسنده , , Eugene P and Balenkova، نويسنده , , Elizabeth S، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
3
From page
8449
To page
8451
Abstract
Substituted homologues of tryptamines were synthesized in one step in high yields under mild conditions. The key intermediates are arylhydrazones of 6-aminohexanones, which undergo Fischer rearrangement readily in glacial acetic acid. An easy and ready for scale-up procedure is developed and formerly unknown 2-substituted dihomotryptamines are obtained.
Keywords
indolisation , Biologically active compounds , Fischer reaction , amino ketones
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1659077
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