Title of article
Efficient syntheses of 2-(2,6-dichloro-4-trifluoromethyl-phenyl)tetrahydrocyclopenta, tetrahydrothiopyrano, hexahydrocycloheptapyrazoles and tetrahydroindazoles
Author/Authors
Meegalla، نويسنده , , Sanath K. and Doller، نويسنده , , Dario and Liu، نويسنده , , Ruiping and Sha، نويسنده , , Deyou and Soll، نويسنده , , Richard M. and Dhanoa، نويسنده , , Dale S.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
4
From page
8639
To page
8642
Abstract
Two methods are described for the regiospecific synthesis of 3,4-fused-cycloalkyl-1-arylpyrazoles; the key step is the reaction between aryl hydrazines and cyclic α-(dimethoxymethyl)ketones. The latter are obtained by BF3-promoted alkylation of ketones with trimethylorthoformate.
Keywords
arylpyrazoles , Synthesis , Boron trifluoride , Alkylation , trimethylorthoformate
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1659182
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