Title of article
Synthetic study of 1,7,9-trideoxypaclitaxel via sinenxan A
Author/Authors
Zhang، نويسنده , , Meng and Yin، نويسنده , , Dali and Guo، نويسنده , , Ji-Yu and Liang، نويسنده , , Xiao-Tian، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
4
From page
9425
To page
9428
Abstract
Sinenxan A, a biosynthetic taxane, was converted into compound 9, a key intermediate of 1,7,9-trideoxypaclitaxel. Two special steps in this transformation are worthy of note: (1) regioselective removal of C-5-acetyl; and (2) stereoselective reduction of the 13-carbonyl group by transannular assistance from the C-4-hydroxyl.
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1659643
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