Title of article
The biocatalytic conversion of 8-hydroxymanzamine A to manzamine A
Author/Authors
Kasanah، نويسنده , , Noer and Rao، نويسنده , , Karumanchi V. and Yousaf، نويسنده , , Muhammad and Wedge، نويسنده , , David E. and Hamann، نويسنده , , Mark T.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
3
From page
1291
To page
1293
Abstract
The selective dehydroxylation of 8-hydroxymanzamine A (1) to form manzamine A (2) can be completed by fermentation with Fusarium solani or Streptomyces seokies. This unique biocatalytic conversion is important due to the fact that manzamine A has more desirable biological activity when assayed in a murine model against malaria.
Keywords
8-hydroxymanzamine A , selective dehydroxylation , Fusarium Solani , Streptomyces seokies
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1660564
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