Title of article
Palladium(0)-catalyzed Mizoroki–Heck reaction and Rh(I)-catalyzed asymmetric hydrogenation of polymer-supported dehydroalanine system
Author/Authors
Doi، نويسنده , , Takayuki and Fujimoto، نويسنده , , Nobuaki and Watanabe، نويسنده , , Jun and Takahashi، نويسنده , , Takashi، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
5
From page
2161
To page
2165
Abstract
We have developed a practical route for the synthesis of peptides containing unnatural amino acids. Mizoroki–Heck reaction of polymer-supported dehydroalanine, followed by asymmetric hydrogenation was accomplished using Pd(0) and Rh(I)–DuPHOS catalysts, respectively, leading to 36 dipeptides containing phenylalanine derivatives with high stereocontrol.
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1661092
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