Title of article
Chemoenzymatic polymer-supported liquid phase synthesis of glucose γ-aminobutyric ester
Author/Authors
de Torres، نويسنده , , Carmen and Fernلndez-Mayoralas، نويسنده , , Alfonso، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
3
From page
2383
To page
2385
Abstract
A concise, polymer-supported solution synthesis of 6-O-(γ-aminobutyryl)-d-glucose has been achieved. Glucose was attached to polyethylene glycol monomethyl ether (MPEG) through an α,α′-dioxyxylyl diether linker, and, subsequently, the HO-6 hydroxyl of the glucose was regioselectively esterified with γ-aminobutyric acid by a lipase-catalyzed reaction.
Keywords
glucose ?-aminobutyric acid ester , polymer-supported solution synthesis , Lipase , regioselective acylation
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1661218
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