Title of article
Facile N-1 protection of cyclam, cyclen and 1,4,7-triazacyclononane
Author/Authors
Yang، نويسنده , , Wen and Giandomenico، نويسنده , , Christen M. and Sartori، نويسنده , , Michael and Moore، نويسنده , , Dennis A.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
3
From page
2481
To page
2483
Abstract
An exceptionally high yielding method for the tri-protection of cyclam and cyclen using ethyl trifluoroacetate is described. The selective reaction also applies to the di-protection of 1,4,7-triazacyclononane. The application of this method in the synthesis of AMD3100, a clinical candidate for stem cell mobilization is presented.
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1661281
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