Title of article
N-Alkylation of amines with alcohols catalyzed by a Cp*Ir complex
Author/Authors
Fujita، نويسنده , , Ken-ichi and Li، نويسنده , , Zhenzi and Ozeki، نويسنده , , Naohiro and Yamaguchi، نويسنده , , Ryohei، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
4
From page
2687
To page
2690
Abstract
A new effective catalytic system consisting of [Cp*IrCl2]2/K2CO3 (Cp*=pentamethylcyclopentadienyl) for the N-alkylation of primary amines with alcohols has been developed. As an example, the reaction of aniline with benzyl alcohol in the presence of [Cp*IrCl2]2 (5.0 mol%Ir) and K2CO3 (5.0 mol%) in toluene at 110°C for 17 h gave benzylaniline in an isolated yield of 88%.
Keywords
Iridium catalyst , N-Alkylation , Hydrogen transfer , alcohol , Amine
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1661416
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