Title of article
Efficient and convergent stereocontrolled spiroannulation of ketones
Author/Authors
Markَ، نويسنده , , Istvلn E. and Vanherck، نويسنده , , Jean-Christophe and Ates، نويسنده , , Ali and Tinant، نويسنده , , Bernard and Declercq، نويسنده , , Jean-Paul، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
4
From page
3333
To page
3336
Abstract
Upon treatment with tBuOK/H2O, a variety of ω-halo-β-keto-ketals undergo smooth cyclisation, affording in excellent yields mono-protected [n,m] spiro bicyclic diketones. This transformation is highly stereoselective producing, in all cases, the diastereoisomerically pure spiro derivatives.
Keywords
stereocontrol , orthoesters , spirobicycle , annulation , Alkylation
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1661791
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