Title of article
Asymmetric oxazaborolidine-catalyzed reduction of prochiral ketones with N-tert-butyl-N-trimethylsilylamine–borane
Author/Authors
Huertas، نويسنده , , Ramَn E. and Corella، نويسنده , , Joseph A. and Soderquist، نويسنده , , John A.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
3
From page
4435
To page
4437
Abstract
Employing N-tert-butyl-N-trimethylsilylamine-borane (1) as the borane source and 5–10% (R)-Me-CBS (2), the oxazaborolidine-catalyzed reduction of representative aryl and aliphatic ketones was carried out obtaining the corresponding alcohols (3) in 83–89% isolated yields and 69–98% ee.
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1662441
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