• Title of article

    Asymmetric oxazaborolidine-catalyzed reduction of prochiral ketones with N-tert-butyl-N-trimethylsilylamine–borane

  • Author/Authors

    Huertas، نويسنده , , Ramَn E. and Corella، نويسنده , , Joseph A. and Soderquist، نويسنده , , John A.، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2003
  • Pages
    3
  • From page
    4435
  • To page
    4437
  • Abstract
    Employing N-tert-butyl-N-trimethylsilylamine-borane (1) as the borane source and 5–10% (R)-Me-CBS (2), the oxazaborolidine-catalyzed reduction of representative aryl and aliphatic ketones was carried out obtaining the corresponding alcohols (3) in 83–89% isolated yields and 69–98% ee.
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2003
  • Journal title
    Tetrahedron Letters
  • Record number

    1662441