Title of article
Pyridazines. Part 34: Retro-ene-assisted palladium-catalyzed synthesis of 4,5-disubstituted-3(2H)-pyridazinones
Author/Authors
Sotelo، نويسنده , , Eddy and Coelho، نويسنده , , Alberto and Raviٌa، نويسنده , , Enrique، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
4
From page
4459
To page
4462
Abstract
The efficient one-pot bis-functionalization of the 4,5-positions of the 3-pyridazinone ring has been performed using Suzuki, Sonogashira and Stille cross-coupling reactions assisted by a retro-ene fragmentation. This route allows access in a shorter synthetic sequence to several pharmacologically useful 3(2H)-pyridazinones.
Keywords
Pyridazinone , ene-adducts , PALLADIUM , Catalysis
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1662457
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