Title of article
A divergent approach to apoptolidin and FD-891: asymmetric preparation of a common intermediate
Author/Authors
Chng، نويسنده , , Shu-Sin and Xu، نويسنده , , Jia and Loh، نويسنده , , Teck-Peng، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
4
From page
4997
To page
5000
Abstract
Biologically active Apoptolidin and FD-891 have structural similarity in their macrocyclic cores. Asymmetric preparation of a common intermediate in the total synthesis of these two macrolides is presented. A modified Masuyama Sn-allylation was employed to control the relative stereochemistry in the synthesis of the intermediate.
Keywords
apoptolidin , FD-891 , divergent synthesis
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1662770
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