Title of article
A new synthesis of 1,3-thiazines and their transformation into 1-substituted-6-alkyluracils by extrusion of carbonyl sulfide
Author/Authors
Yuskovets، نويسنده , , Valera N. and Ivin، نويسنده , , Boris A.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
2
From page
5279
To page
5280
Abstract
A simple synthesis of 5-acyl-4-hydroxy-3,6-dihydro-2H-1,3-thiazine-2,6-diones from malonic acid, potassium thiocyanate and acid anhydrides is described. A new, general, regioselective method for the synthesis of 1-substituted-6-alkyluracils by the reaction of these thiazines with primary alkyl and arylamines is reported.
Keywords
3-Thiazine , 6-methyluracil , Thiocyanate , Malonic acid , Carbonyl sulfide , 3-disubstituted urea , 1 , 1
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1662952
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