• Title of article

    A novel urea-linked dipodal naphthalene-based fluorescent sensor for Hg(II) and its application in live cell imaging

  • Author/Authors

    Tayade، نويسنده , , Kundan and Bondhopadhyay، نويسنده , , Banashree and Basu، نويسنده , , Anupam and Chaitanya، نويسنده , , G. Krishna and Sahoo، نويسنده , , Suban K. and Singh، نويسنده , , Narinder and Attarde، نويسنده , , Sanjay and Kuwar، نويسنده , , Anil، نويسنده ,

  • Issue Information
    ماهنامه با شماره پیاپی سال 2014
  • Pages
    7
  • From page
    16
  • To page
    22
  • Abstract
    A novel cell-permeable urea-linked dipodal naphthalene-based fluorescent receptor 1 (1,1׳-(1,5,5-trimethyl-3-oxocyclohexane-1,2-diyl)bis(3-(naphthalen-2-yl)urea) was designed and synthesized. The cation recognition ability of 1 was evaluated with a library of metal ions in DMSO/H2O (9:1, v/v). The receptor showed a selective chromogenic and fluorescent turn-off response towards Hg2+ among the surveyed metal ions. The developed sensor was successfully applied to image intracellular Hg2+ in living cells and also for the determination of Hg2+ content in real water samples. Moreover, the DFT calculations were performed to complement the experimental evidences.
  • Keywords
    Cellular imaging , Real sample analysis , DFT , fluorescent sensor , Hg2+ , Turn-off
  • Journal title
    Talanta
  • Serial Year
    2014
  • Journal title
    Talanta
  • Record number

    1670429