Title of article
Regioselective alcoholysis of silybin A and B acetates with lipases
Author/Authors
Purchartov?، نويسنده , , Kate?ina and Marhol، نويسنده , , Petr and Ga??k، نويسنده , , Radek and Monti، نويسنده , , Daniela and Riva، نويسنده , , Sergio and Kuzma، نويسنده , , Marek and K?en، نويسنده , , Vladim?r، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2011
Pages
5
From page
119
To page
123
Abstract
Large screening identified lipase AK to be capable of the selective deacetylation of pentaacetyl silybins A and B to yield 3,5,20,23-tetra-O-acetyl-silybins A and B, and 3,20,23-tri-O-acetyl-silybins A and B, respectively. Deacetylation occurred at phenolic OH groups, only. These new compounds prepared from the optically pure silybins can serve as new stereochemically pure synthons for selective silybin modifications.
Keywords
Silymarin , Silibinin , Lipase , Silybin B , deacylation
Journal title
Journal of Molecular Catalysis B Enzymatic
Serial Year
2011
Journal title
Journal of Molecular Catalysis B Enzymatic
Record number
1715253
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