Enzymatic modification of the sugar moieties of natural glycosides

Glycosides of various classes of natural products are widely distributed in nature. Many of these compounds are pharmacologically important molecules or possess other interesting properties and, quite often, their sugar moieties are acylated with aliphatic and aromatic acids. ent years the regioselectivity of lipases and proteases has been exploited by different research groups for the synthesis, in organic solvents, of specific esters of natural glycosides. The selectivity of the β-1,4-galactosyl-transferase (GalT) from bovine colostrum, has also been investigated, aiming to produce new glycosyl derivatives of these compounds. plications of these two bio-transformations will be discussed in this review.