Title of article
Stereoselective synthesis of aryl γ,δ-unsaturated β-hydroxyesters by ketoreductases
Author/Authors
Dai، نويسنده , , Zhipeng and Guillemette، نويسنده , , Kate and Green، نويسنده , , Thomas K.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2013
Pages
6
From page
264
To page
269
Abstract
The biocatalytic reduction of aryl γ,δ-unsaturated-β-ketoesters was evaluated utilizing 24 different commercially available ketoreductases. In all cases, both (R) and (S)-enantiomers of γ,δ-unsaturated β-hydroxyesters were synthesized by one or more ketoreductases in excellent optical purity and yields.
Keywords
Ketoreductases , Ketoesters , enzymes , Enantioselectivity
Journal title
Journal of Molecular Catalysis B Enzymatic
Serial Year
2013
Journal title
Journal of Molecular Catalysis B Enzymatic
Record number
1718308
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