Title of article
Biomedical applications of boronic acid polymers
Author/Authors
JERRY WELKENHUYSEN-GYBELS JAAK BILLIET BART CAMBRE، نويسنده , , Jennifer N. and Sumerlin، نويسنده , , Brent S.، نويسنده ,
Issue Information
دوهفته نامه با شماره پیاپی سال 2011
Pages
13
From page
4631
To page
4643
Abstract
Boron-containing organic compounds have found widespread use in synthetic organic chemistry. More recently, boronic acid-containing polymers have proven valuable in a variety of biomedical applications, including the treatment of HIV, obesity, diabetes, and cancer. However, as compared to many other classes of functional polymers, boronic acid-containing (co)polymers remain underutilized, despite their unique reactivity, solubility, and responsive nature. This Feature Article highlights research in this area, with particular focus on recent developments in synthesis, processing, and materials development that have enabled the preparation of new biomaterials. In addition to providing an overview to the current state of the art, we emphasize the versatility of boronic acid polymers and suggest routes for their further employment in other potential biomedical applications.
Keywords
Boronic Acid , Lipase inhibition , Glucose sensors , Insulin delivery , HIV inhibition
Journal title
Polymer
Serial Year
2011
Journal title
Polymer
Record number
1738090
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