• Title of article

    A heat-activated and thermoresistant telomerase activity in Leishmania major Friedlin

  • Author/Authors

    Galindo، نويسنده , , Maria Mercedes and Rodriguez، نويسنده , , Evelyn and Rojas، نويسنده , , Maria Gabriela and Figarella، نويسنده , , Katherine and Campelo، نويسنده , , Riward and Ramيrez، نويسنده , , Jose Luis، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2009
  • Pages
    4
  • From page
    86
  • To page
    89
  • Abstract
    Here we studied the telomerase activity of the human parasite Leishmania major. In this organism we have detected a high activity of this enzyme once several parameters such as heat activation, sequence of extension primer, and protein concentration are adjusted. The activity was not only heat activated, but also very resistant to heat denaturation. We believe L. major telomerase is an important activity and it may provide an adequate drug therapy target.
  • Keywords
    Thermoresistant , Highly active , Leishmania telomerase
  • Journal title
    Acta Tropica
  • Serial Year
    2009
  • Journal title
    Acta Tropica
  • Record number

    1740375