Perfectionism and physical disability predict depression in multiple sclerosis

AbstractObjective lationship between depression and physical disability in multiple sclerosis (MS) is unclear. This investigation examines the interaction between disability and perfectionism in predicting depression in MS. s ipants (n = 51) completed the Frost Multidimensional Perfectionism Scale (FMPS), the Chicago Multiscale Depression Inventory (CMDI), and the Expanded Disability Status Scale (EDSS). s sion revealed that the FMPS × EDSS interaction predicted depression above the variance predicted by each variable alone. Perfectionism predicted depression at high levels of disability. sion sults suggest a means of reconciling inconsistent findings regarding physical disability and depression in MS and offer a potential target for psychotherapy.