• Title of article

    Anti-rat CD45RA monoclonal antibodies cross-react with glucagon

  • Author/Authors

    Kaino، نويسنده , , Yukikazu and Ito، نويسنده , , Takuo and Hirai، نويسنده , , Hiroki and Kida، نويسنده , , Kaichi، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2000
  • Pages
    7
  • From page
    151
  • To page
    157
  • Abstract
    Summary at CD45RA monoclonal antibody (MAb) has been used as a marker for rat B-lymphocytes (B-cells). When we applied the MAb to identify B-lymphocytes among immune cells infiltrating pancreatic islets of the BB rat, which is an animal model for human type 1 diabetes mellitus, a subpopulation of islet cells was immunostained as well. Our immunohistochemical investigations demonstrated that the stained islet cells are pancreatic α-cells and the MAb cross-reacts with glucagon.
  • Keywords
    B-lymphocyte , glucagon , Type 1 Diabetes Mellitus , BB rat , cross-reactivity , MRC OX-33 , anti-rat CD45RA antibody
  • Journal title
    Acta Histochemica
  • Serial Year
    2000
  • Journal title
    Acta Histochemica
  • Record number

    1758817

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1758817