Title of article
Photodynamic therapy of photofrin II and excimer dye laser on experimental tumors
Author/Authors
Tanaka، نويسنده , , Motohiro and Uchibayashi، نويسنده , , Tadao and Obata، نويسنده , , Tohru and Sasaki، نويسنده , , Takuma، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1995
Pages
7
From page
163
To page
169
Abstract
Photodynamic therapy (PDT) by combination of photofrin II and excimer dye laser was evaluated for its usefulness in experimental tumors. High antitumor effects of PDT on sarcoma 180 solid type were obtained when PDT was performed with laser irradiation at an energy of 50 or 100 J/cm2 (40 or 80 Hz, 4 mJ/pulse) 48 h after i.v. administration of photofrin II at a dose of 25 mg/kg. Under the same conditions, the antitumor effects of PDT on murine Lewis lung carcinoma, human fibrosarcoma HT-1080 and human bladder transitional cell carcinoma KK-47 were also observed. These results suggest that clinical application of PDT with photofrin II and excimer dye laser might be useful.
Keywords
Photofrin II , Antitumor activity , Excimer dye laser , photodynamic therapy
Journal title
Cancer Letters
Serial Year
1995
Journal title
Cancer Letters
Record number
1796578
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