Title of article
The antitumoral compound Kahalalide F acts on cell lysosomes
Author/Authors
Garcيa-Rocha، نويسنده , , Mar and Bonay، نويسنده , , Pedro C. Avila، نويسنده , , Jesْs، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
8
From page
43
To page
50
Abstract
The target for the antitumoral peptidic drug, Kahalalide F, has been studied in cultured cells. In the presence of the compound, the cells became impressively swollen, showing the formation of large vacuoles. The formation of these vacuoles appears to be the consequence of changes in lysosomal membranes. Thus, lysosomes are a target for Kahalalide F action.
Keywords
Kahalalide F , lysosomes , Cytoskeleton , Golgi apparatus , endoplasmic reticulum
Journal title
Cancer Letters
Serial Year
1996
Journal title
Cancer Letters
Record number
1797658
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