Title of article
Regulation by calcium of the synthesis of 1,25-dihydroxyvitamin D3 and 24,25-dihydroxyvitamin D3 in Walker 256 carcinosarcoma cells: comparison with synthesis regulation from renal phenotype cells (LLC-PK1)
Author/Authors
Municio del Campo، نويسنده , , M.Jesْs and Villameytide، نويسنده , , M.Luisa Traba، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1998
Pages
7
From page
147
To page
153
Abstract
The aim of this work was to study the regulation by calcium of the synthesis of 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) and 24,25-dihydroxyvitamin D3 (24,25(OH)2D3) in Walker 256 carcinosarcoma (W256) cells compared to renal phenotype LLC-PK1 cells. We have detected synthesis of 1,25(OH)2D3 and 24,25(OH)2D3 in W256 cells. Levels of 1,25(OH)2D3 in W256 were similar to those of LLC-PK1 cells. Levels of 24,25(OH)2D3 were higher in W256 than in LLC-PK1 cells. High levels of calcium inhibited 1,25(OH)2D3 synthesis in LLC-PK1 cells but not in W256 cells.
Keywords
Walker 256 carcinosarcoma cells , LLC-PK1 cells , 25-Dihydroxyvitamin D3 , 25-Dihydroxyvitamin D3 , Calcium , 24 , 1
Journal title
Cancer Letters
Serial Year
1998
Journal title
Cancer Letters
Record number
1799863
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